Tilman Brummer : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (46)
Les plus populaires
Liste
- Liste
- Tableau

1

BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines

Herr, Ricarda, Halbach, Sebastian, Heizmann, Miriam, Busch, Hauke, Boerries, Melanie, Brummer, Tilman

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2018

2

Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation

Beneker, Chad M., Rovoli, Magdalini, Kontopidis, George, Röring, Michael, Galda, Simeon, Braun, Sandra, Brummer, Tilman, McInnes, Campbell

Journal:

Journal of Medicinal Chemistry

Année:

2019

Fichier:

PDF, 7.34 MB

2019

3

RAF kinase dimerization: implications for drug discovery and clinical outcomes

Brummer, Tilman, McInnes, Campbell

Journal:

Année:

2020

Fichier:

PDF, 1.63 MB

2020

4

Adenosine and cAMP are potent inhibitors of the NF-κB pathway downstream of immunoreceptors

Susana Minguet, Michael Huber, Lisa Rosenkranz, Wolfgang W. A. Schamel, Michael Reth, Tilman Brummer

Journal:

European Journal of Immunology

Année:

2005

Langue:

english

Fichier:

PDF, 328 KB

english, 2005

5

Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development

Emmy D.G. Fleuren, Sandra O'Toole, Ewan K. Millar, Catriona McNeil, Elena Lopez-Knowles, Alice Boulghourjian, David R. Croucher, Daniel Schramek, Tilman Brummer, Josef M. Penninger, Robert L. Sutherla

Journal:

International Journal of Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2010

6

Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma

Anja E. Eisenhardt, Heike Olbrich, Michael Röring, Wibke Janzarik, Ton Nu Van Anh, Huriye Cin, Marc Remke, Hendrik Witt, Andrey Korshunov, Stefan M. Pfister, Heymut Omran, Tilman Brummer

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 809 KB

english, 2011

7

Function, regulation and pathological roles of the Gab/DOS docking proteins

Franziska U Wöhrle, Roger J Daly, Tilman Brummer

Journal:

Cell Communication and Signaling

Année:

2009

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2009

8

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

Ricarda Herr, Franziska U Wöhrle, Christina Danke, Christian Berens, Tilman Brummer

Journal:

Cell Communication and Signaling

Année:

2011

Langue:

english

Fichier:

PDF, 7.77 MB

english, 2011

9

Docking proteins

Tilman Brummer, Carsten Schmitz-Peiffer, Roger J. Daly

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 303 KB

english, 2010

10

Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

Brummer, Tilman, Larance, Mark, Abreu, Maria Teresa Herrera, Lyons, Ruth J, Timpson, Paul, Emmerich, Christoph H, Fleuren, Emmy D G, Lehrbach, Gillian M, Schramek, Daniel, Guilhaus, Michael

Journal:

The EMBO Journal

Année:

2008

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2008

11

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1

Jeffrey, Kate L, Brummer, Tilman, Rolph, Michael S, Liu, Sue M, Callejas, Nuria A, Grumont, Raelene J, Gillieron, Corine, Mackay, Fabienne, Grey, Shane, Camps, Montserrat

Journal:

Nature Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 601 KB

english, 2006

12

The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion

Flemming, Alexandra, Brummer, Tilman, Reth, Michael, Jumaa, Hassan

Journal:

Nature Immunology

Année:

2002

Langue:

english

Fichier:

PDF, 415 KB

english, 2002

13

Feedback regulation of lymphocyte signalling

Reth, Michael, Brummer, Tilman

Journal:

Nature Reviews Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2004

14

Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf

Brummer, Tilman, Naegele, Heike, Reth, Michael, Misawa, Yukiko

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 351 KB

english, 2003

15

A revised and complete map of the chicken c-mil/raf-1 locus

Brummer, Tilman, Stéhelin, Dominique, Misawa, Yukiko, Reth, Michael

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 133 KB

english, 2004

16

How to Grb2 a Gab

Franziska U. Wöhrle, Roger J. Daly, Tilman Brummer

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 281 KB

english, 2009

17

The immunohistochemical staining pattern of Gab2 correlates with distinct stages of chronic myeloid leukemia

Konrad Aumann, Silke Lassmann, Anja Schöpflin, Annette M. May, Franziska U. Wöhrle, Robert Zeiser, Cornelius F. Waller, Dieter Hauschke, Martin Werner, Tilman Brummer

Journal:

Human Pathology

Année:

2011

Langue:

english

Fichier:

PDF, 846 KB

english, 2011

18

DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs

Kate I. Patterson, Tilman Brummer, Roger J. Daly, Philippa M. O'Brien

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2010

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2010

19

A generic strategy for pharmacological caging of growth factors for tissue engineering

Karlsson, Maria, Lienemann, Philipp S., Sprossmann, Natallia, Heilmann, Katharina, Brummer, Tilman, Lutolf, Matthias P., Ehrbar, Martin, Weber, Wilfried

Journal:

Chemical Communications

Année:

2013

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2013

20

Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans

Weinberg, Florian, Schulze, Ekkehard, Fatouros, Chronis, Schmidt, Enrico, Baumeister, Ralf, Brummer, Tilman

Journal:

Gene Expression Patterns

Année:

2014

Langue:

english

Fichier:

PDF, 3.02 MB

english, 2014

21

Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines

Boerries, Melanie, Herr, Ricarda, Brummer, Tilman, Busch, Hauke

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2015

22

Differential tyrosine phosphorylation controls the function of CNK1 as a molecular switch in signal transduction

Fischer, Adrian, Brummer, Tilman, Warscheid, Bettina, Radziwill, Gerald

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2015

23

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

Lehmann, Waltraut, Mossmann, Dirk, Kleemann, Julia, Mock, Kerstin, Meisinger, Chris, Brummer, Tilman, Herr, Ricarda, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 3.49 MB

english, 2016

24

BRAF inhibitors in colorectal cancer: Toward a differentiation therapy?

Herr, Ricarda, Brummer, Tilman

Journal:

Molecular & Cellular Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2015

25

Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

Halbach, Sebastian, Hu, Zehan, Gretzmeier, Christine, Ellermann, Julia, Wöhrle, Franziska U., Dengjel, Jörn, Brummer, Tilman

Journal:

Cell Communication and Signaling

Année:

2016

Langue:

english

Fichier:

PDF, 2.19 MB

english, 2016

26

A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells

Preca, Bogdan-Tiberius, Bajdak, Karolina, Mock, Kerstin, Sundararajan, Vignesh, Pfannstiel, Jessica, Maurer, Jochen, Wellner, Ulrich, Hopt, Ulrich T., Brummer, Tilman, Brabletz, Simone, Brabletz, Thom

Journal:

International Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 845 KB

english, 2015

27

Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface

Bier, David, Bartel, Maria, Sies, Katharina, Halbach, Sebastian, Higuchi, Yusuke, Haranosono, Yu, Brummer, Tilman, Kato, Nobuo, Ottmann, Christian

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2016

28

B-Raf activation loop phosphorylation revisited

Köhler, Martin, Brummer, Tilman

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2016

29

UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome

Maier, Kristin, He, Yinghong, Wölfle, Ute, Esser, Philipp R., Brummer, Tilman, Schempp, Christoph, Bruckner-Tuderman, Leena, Has, Cristina

Journal:

Human Molecular Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2016

30

Exometabolom analysis of breast cancer cell lines: Metabolic signature

Willmann, Lucas, Erbes, Thalia, Halbach, Sebastian, Brummer, Tilman, Jäger, Markus, Hirschfeld, Marc, Fehm, Tanja, Neubauer, Hans, Stickeler, Elmar, Kammerer, Bernd

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2015

31

The Versatile Role of Gab1 in the Circulatory System

W^|^ouml, hrle, Franziska U., Halbach, Sebastian, Brummer, Tilman

Journal:

Circulation Journal

Année:

2012

Langue:

english

Fichier:

PDF, 310 KB

english, 2012

32

Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition

Diedrich, Britta, Rigbolt, Kristoffer TG, Röring, Michael, Herr, Ricarda, Kaeser‐Pebernard, Stephanie, Gretzmeier, Christine, Murphy, Robert F, Brummer, Tilman, Dengjel, Jörn

Journal:

The EMBO Journal

Année:

2017

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2017

33

MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib

Young, Adelaide I. J., Law, Andrew M. K., Castillo, Lesley, Chong, Sabrina, Cullen, Hayley D., Koehler, Martin, Herzog, Sebastian, Brummer, Tilman, Lee, Erinna F., Fairlie, Walter D., Lucas, Morghan C

Journal:

Breast Cancer Research

Année:

2016

Langue:

english

Fichier:

PDF, 7.03 MB

english, 2016

34

CDK9‐mediated phosphorylation controls the interaction of TIP60 with the transcriptional machinery

Brauns‐Schubert, Prisca, Schubert, Florian, Wissler, Manuela, Weiss, Martina, Schlicher, Lisa, Bessler, Simon, Safavi, Mariam, Miething, Cornelius, Borner, Christoph, Brummer, Tilman, Maurer, Ulrich

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2018

35

RAF-Inhibitoren; RAF inhibitors;

Utikal, Jochen, Brummer, Tilman, Zenz, Thorsten

Journal:

Année:

2018

Langue:

german

Fichier:

PDF, 707 KB

german, 2018

36

EGFR-Targeted TRAIL and a Smac Mimetic Synergize to Overcome Apoptosis Resistance in KRAS Mutant Colorectal Cancer Cells

Möller, Yvonne, Siegemund, Martin, Beyes, Sven, Herr, Ricarda, Lecis, Daniele, Delia, Domenico, Kontermann, Roland, Brummer, Tilman, Pfizenmaier, Klaus, Olayioye, Monilola A., Souglakos, John

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2014

37

Specific role of RhoC in tumor invasion and metastasis

Lang, Sarah, Busch, Hauke, Boerries, Melanie, Brummer, Tilman, Timme, Sylvia, Lassmann, Silke, Aktories, Klaus, Schmidt, Gudula

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 7.45 MB

english, 2017

38

Specific role of RhoC in tumor invasion and metastasis

Lang, Sarah, Busch, Hauke, Boerries, Melanie, Brummer, Tilman, Timme, Sylvia, Lassmann, Silke, Aktories, Klaus, Schmidt, Gudula

Journal:

Année:

2017

Fichier:

PDF, 7.45 MB

2017

39

Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL

Schorch, Björn, Heni, Hannah, Zahaf, Nour-Imene, Brummer, Tilman, Mione, Marina, Schmidt, Gudula, Papatheodorou, Panagiotis, Aktories, Klaus

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.66 MB

english, 2018

40

Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL

Schorch, Björn, Heni, Hannah, Zahaf, Nour-Imene, Brummer, Tilman, Mione, Marina, Schmidt, Gudula, Papatheodorou, Panagiotis, Aktories, Klaus

Journal:

Année:

2018

Fichier:

PDF, 3.66 MB

2018

41

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia

Sies, Katharina, Spohr, Corinna, Gründer, Albert, Todorova, Rumyana, Uhl, Franziska Maria, Huber, Julia, Zeiser, Robert, Pahl, Heike Luise, Becker, Heiko, Aumann, Konrad, Brummer, Tilman, Halbach, Seb

Journal:

Année:

2019

Fichier:

PDF, 1.08 MB

2019

42

Gab2 is Essential for Transformation by FLT3-ITD in Acute Myeloid Leukemia

Sies, Katharina, Spohr, Corinna, Gründer, Albert, Todorova, Rumyana, Uhl, Franziska Maria, Huber, Julia, Zeiser, Robert, Pahl, Heike Luise, Becker, Heiko, Aumann, Konrad, Brummer, Tilman, Halbach, Seb

Journal:

Année:

2019

Fichier:

PDF, 1.09 MB

2019

43

Functional coupling of presequence processing and degradation in human mitochondria

KÃ¼cÃ¼kkÃ¶se, Cansu, Taskin, Asli Aras, Marada, Adinarayana, Brummer, Tilman, Dennerlein, Sven, VÃ¶gtle, FriederikeâNora

Journal:

Année:

2020

Fichier:

PDF, 1.44 MB

2020

44

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

Reischmann, Nadine, Andrieux, Geoffroy, Griffin, Ricarda, Reinheckel, Thomas, Boerries, Melanie, Brummer, Tilman

Journal:

Année:

2020

Fichier:

PDF, 9.39 MB

2020

45

Aberrant B-Raf Signaling in Human Cancer â 10 Years from Bench to Bedside

Roring, Michael, Brummer, Tilman

Journal:

Critical Reviews™ in Oncogenesis

Année:

2012

Fichier:

PDF, 1.44 MB

2012

46

Immune modulatory effects of oncogenic KRAS in cancer

Hamarsheh, Shaimaâa, GroÃ, Olaf, Brummer, Tilman, Zeiser, Robert

Journal:

Nature Communications

Année:

2020

Fichier:

PDF, 1.07 MB

2020